Black Hash – Afghani Hybrid

Research on CBN is scarce, especially when it comes to human clinical trials, but some preclinical studies suggest CBN can be a therapeutic substance in a few ways.

Drowsiness is a potential side effect of CBN, especially when combined with CBD.  Consumers often turn to CBN products for assistance with sleep and relaxation, in which cases these effects might be considered potential benefits by the user.

CBN may also have have anti-inflammatory activity that could be “beneficial in healing chronic wounds where healing has been prevented by prolonged inflammation,” says Eric Hsu, senior vice president of pre-clinical research and development at InMed Pharmaceuticals.

According to research conducted by InMed Pharmaceuticals, CBN may be useful in treating eye conditions like glaucoma, which causes vision loss and blindness as it damages the optic nerve in the back of the eye. High eye pressure is associated with glaucoma, and lowering that pressure is a known way to slow the condition.

In addition, a 2019 study on rats found CBN—as well as CBD and a mix of the two cannabinoids—decreased muscle sensitization. The researchers suggest CBN could provide pain relief for chronic muscle pain disorders, such as temporomandibular disorders (pain in the jaw muscles, joints and nerves) and fibromyalgia (a condition that causes pain all over the body), but clinical studies have yet to test this theory.

Myrcene, better known as the active sedating principle of hops and lemongrass, is also found in basil, mangos, and of course, cannabis.  Myrcene synergies the activities  terpenes and other compounds in a variety of ways. One mechanism that would be of particular note in cannabis is its claimed effect on the permeability of cell membranes, particularly the blood–brain barrier (BBB), increasing transport of the cannabinoids for use by the body.  Myrcene has been shown to enhance transdermal absorption and it has an analgesic effect. At higher  doses, myrcene in mice was a sedative comparable to phenobarbital. It also shows powerful anti-inflammatory and anticatabolic effects in a human chondrocyte model of osteoarthritis.

While delta 9 is naturally occurring in large amounts, delta 8 is only found in trace amounts. Both activating a CB1 and CB2 receptors, they help the endocannabinoid system keep things like mood, memory, sleep, pain, and appetite in check. While delta 9 has a higher affinity to the CB1 receptor than delta 8, creating less of a psychoactive experience with Delta 8.

Delta 8 has a long list of health benefits! It’s been shown to reduce nausea, pain, vomiting, and appetite loss while protecting nerve cells and improving mood.

If you have never taken any kind of THC before, we suggest a starting dose of 10-25mg. Wait at least 45 minutes before redosing. The effects from Delta 8 can last anywhere from 2-12 hours depending on the person and how much was administered

One of the most common mistakes that people make when they are trying out Delta 8 for the first time is taking too much. Too much Delta 8 may cause dry mouth, dizziness, muscle impairment, reduced motor control, vomiting, sleep, and change in sensory perception. In most cases, the best thing to do if you have had too much Delta 8 is to sleep it off. Taking CBD is also known to counteract the effects of Delta 8. However, you should get medical attention if side effects go above a bad hangover type feel.